Fisetin - 400 mg x 60 capsules - 98% Pure

Name: Fisetin - 400 mg x 60 capsules - 98% Pure
Brand: Augment Life
SKU: FS40060
Price: 72.0 EUR
Availability: InStock

Fisetin - 400 mg x 60 capsules - 98% Pure

€72,00

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Fisetin is a powerful flavonoid in fruits like apples, strawberries, and grapes. With its strong antioxidant properties, fisetin offers the body protection from free radicals and oxidative stress. High levels of oxidative stress damage our DNA, and can lead to the development of many neurological and metabolic diseases, as well as cancer. By protecting us from free radicals, fisetin reduces inflammation and cardiovascular risk and supports healthy aging, longevity, and brain health^1,2. Early research on fisetin shows its potential in anticancer therapy, as well as protection from chemotherapeutical damage³. Fisetin is usually taken up in doses of 200-500 mg per day. Fisetin is considered safe, and so far, no significant side effects have been reported⁴.

References

Khan N, Syed DN, Ahmad N, Mukhtar H. Fisetin: a dietary antioxidant for health promotion. Antioxid Redox Signal. 2013 Jul 10;19(2):151-62. doi: 10.1089/ars.2012.4901. Epub 2012 Dec 18. PMID: 23121441; PMCID: PMC3689181.
Ahmad A, Ali T, Rehman SU, Kim MO. Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment. J Clin Med. 2019 Jun 14;8(6):850. doi: 10.3390/jcm8060850. PMID: 31207963; PMCID: PMC6616651.
Kumar RM, Kumar H, Bhatt T, Jain R, Panchal K, Chaurasiya A, Jain V. Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics. Pharmaceuticals (Basel). 2023 Jan 28;16(2):196. doi: 10.3390/ph16020196. PMID: 37259344; PMCID: PMC9961076.
Hodgin KS, Donovan EK, Kekes-Szabo S, Lin JC, Feick J, Massey RL, Ness TJ, Younger JW. A Placebo-Controlled, Pseudo-Randomized, Crossover Trial of Botanical Agents for Gulf War Illness: Resveratrol (Polygonum cuspidatum), Luteolin, and Fisetin (Rhus succedanea). Int J Environ Res Public Health. 2021 Mar 3;18(5):2483. doi: 10.3390/ijerph18052483. PMID: 33802381; PMCID: PMC7967624.

Product Specifications

Capsules: 60
Capsule material: HPMC (vegetable glucose)
Contents: Fisetin 98% Pure
Capsule sizes: 400 mg
Container: FSC-certified, responsibly-sourced paper tube
Container dimensions: 60 capsules: 5 cm (diameter), 10 cm (height)
Labels: Coated paper (faster biodegrading)

Benefits

Fisetin has antioxidative and anti-inflammatory properties that can protect the body against oxidative damage and free radicals.
Fisetin's protection against free oxygen radicals supports brain health and cognitive abilities in older age. It also has the ability to reduce cellular markers of aging.
Fisetin shows a lot of potential in preclinical studies, in anticancer therapy and treating chemoresistant tumors, as well as protecting the organism from chemotherapeutic damage.

Efficacy studies

One study (NCT04771611 ) examined the effects of fisetin on frailty, inflammation, and aging in older adults. It was a randomized, double-blind, placebo-controlled trial involving individuals aged 65-90. Participants took ~20 mg/kg/day of fisetin for three consecutive days, every 28 days, over 20 weeks. The results suggested that fisetin reduced markers of inflammation and cellular senescence, potentially improving overall health and reducing frailty in older adults.
A pilot study called the COVFIS-HOME study (NCT04771611) explored whether fisetin could reduce the severity of COVID-19 symptoms and prevent long-term complications. Participants received ~20mg/kg /day of oral fisetin for four days. The trial's results indicated some promise in using fisetin for these purposes, but larger studies are needed to confirm the findings.

There are currently no published clinical trials on fisetin and cancer, but there are several ongoing ones:

Fisetin is being investigated for improving the physical function in postmenopausal women after receiving chemotherapy for stage I–III breast cancer (https://clinicaltrials.gov/ct2/show/NCT05595499).
The efficacy, safety, and tolerability of therapies which include fisetin are being investigated in adult survivors of childhood cancer (https://clinicaltrials.gov/ct2/show/NCT04733534).

Fast Delivery & Hassle Free Returns

Shipping: All orders are shipped with priority, tracking, and insurance. Most shipments take between two and four days to arrive at your door. Please check our shipping policy page to see how long a shipment to your country will take.
Returns: If you change your mind or are unsatisfied with your order, let us know, and we'll send you a return label and refund your payment once the return arrives at our shipping facility. Returns take 1 to 2 weeks at most to process.

Quality Assurance

Stored according to GMP best practices, in a facility with low humidity, <25C, refrigeration as required.
A certified food and chemical analysis lab (BAV Institut) has tested every shipment we received to confirm the purity is as claimed. Please note the lab statement of analysis in our product images slider.
Produced and certified according to ISO 9001, HALAL, and Kosher.

Sustainability

Augment Life cares about sustainability. All supply, packaging, and operational decisions have been made to reduce waste, CO2 footprint, and ensure we take care of our planet.
This product has a CO2 footprint of 183 grams.
This is 100% biodegradable, paper tube, packaging. Made from sustainable and responsible sources. Keep the tube for storing paperclips, or make a craft project with them. If they end up in a river, or the sea, or a landfill they will disintegrate in a few months and become part of the soil and nature. Unlike plastic which will be in our waters and landfills for thousands of years.

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Features of Our Fisetin Capsules

Quality Assurance

Our supplements are produced according to the highest standards in the food supplement industy. With ISO 9001 and ISO 2200 the world leading standards for process management, and precision are maintained to insure you receive the highest quality, purest materials possible.

And to be sure no mistakes have been made, Augment Life sends all its supplements to third-party certified laboratories to verify the purity and quality is as expected.

When to Consume

Ideally at morning time

How to Consume

1 capsule with water

Scent

None, while in capsule.

Details

Color: White

Package Contents: Powder

Packaging Dimensions

Tube Size: 50 mm diameter x 100 mm height.

30 Day Return Policy

To Report A Return:

Please use the Return Report form on our returns page.

Damaged Products:

If you believe your supplement has been damaged we offer a free return in the first 14 calendar days from your original order placement date.

Wrong Item:

If you ordered the wrong item, let us know as soon as possible. To order the correct item, please place a new order. To get a refund for your original order, once we have been notified we'll try to cancel your shipment and send out a new one as soon as possible. If the first product ordered is already en-route, you'll need to send it back as soon as it arrives. Once it has reached our restocking facility we'll be happy to refund your payment to the original payment method used.

Not What You Hoped For:

If none of the other issues above applies to your return reason, please explain as best as possible and we'll do our best to find a solution.

Return Shipping Labels:

Once your return is reported we'll send you a return shipping label. Depending on the reason for your return and the original order we may cover the cost of the return.