How to Take Magnesium Glycinate: Best Time, Forms, and Other Considerations

How to Take Magnesium Glycinate: Best Time, Forms, and Other Considerations

Magnesium glycinate is a popular form of magnesium supplement known for its high bioavailability and gentle effects on the digestive system.  If you're considering adding magnesium glycinate to your routine, understanding the optimal dosage, best time to take it, and other key factors can help you maximize its benefits.

Understanding Magnesium Glycinate

Magnesium is a mineral crucial for hundreds of bodily functions, including muscle and nerve function, energy production, and blood sugar control. Unfortunately, many people don't get enough magnesium from their diet alone.1

Magnesium glycinate combines magnesium with glycine, an amino acid. This pairing offers several advantages:

  • High Absorption: Glycine helps magnesium bypass the digestive system more efficiently, leading to better absorption compared to other forms like magnesium oxide.2
  • Gentler on the Stomach: Unlike some magnesium forms that can cause digestive discomfort, magnesium glycinate is generally well-tolerated, making it a good choice for those with sensitive stomachs.4

Finding the Right Form of Magnesium Glycinate

Magnesium glycinate comes in various forms, including:

  • Capsules: These are the most common type and offer a convenient way to take magnesium glycinate.

  • Powder: This form can be easily mixed into water or juice but may have a slightly bitter taste.

  • Liquid: Liquid magnesium glycinate is readily absorbed but may be less convenient and more expensive than other options.


The recommended dosage of magnesium glycinate depends on several factors, including your age, overall health, and the reason you're taking it.  The National Institutes of Health (NIH) recommends the following daily intakes for adults:1

  • Men 400-420 mg

  • Women 310-320 mg

It's important to consult your doctor to determine the appropriate dosage for you, especially if you have any underlying health conditions or are taking medications.

Best Time to Take Magnesium Glycinate

There's no definitive answer on the best time to take magnesium glycinate.  However, some people find taking it before bed helpful for promoting relaxation and sleep.  Others prefer taking it in the morning to avoid potential digestive side effects.  Ultimately, the best time depends on your individual needs and preferences.

Other Considerations When Taking Magnesium Glycinate

Drug Interactions

Magnesium can interact with certain medications. Discuss magnesium supplementation with your doctor if you're taking any medications.

Potential Side Effects

While generally well-tolerated, high doses of magnesium glycinate can cause diarrhea. However, a 2013 study5 indicated that magnesium glycinate may be less likely to cause diarrhea than other types of magnesium supplements.

Still it would be beneficial to start with a low dose and gradually increase it as needed.

Pregnancy and Breastfeeding

If you're pregnant or breastfeeding, talk to your doctor before taking magnesium glycinate.

Final Words

By understanding how much, when, and how to take magnesium glycinate, you can unlock its numerous benefits. Remember, consulting a healthcare professional is crucial for personalized guidance and ensuring safe and effective supplementation.


  1. Office of Dietary Supplements - magnesium. (n.d.).
  2. Jones, J., MD, & O’Brien, M., MD. (2021). Clinics in Sports Medicine.
  3. Levi, A., & Foxys_Forest_Manufacture/iStock/GettyImages. (2021, October 28). Magnesium: benefits, RDAs, risks, foods and supplements.
  4. Magnesium. (2024, April 12). Retrieved June 5, 2024, from
  5. DiSilvestro, R. A., Joseph, E., Starkoff, B. E., & Devor, S. T. (2013). Magnesium glycinate supplementation in bariatric surgery patients and physically fit young adults. The FASEB Journal, 27(S1).
Back to blog

Leave a comment

Please note, comments need to be approved before they are published.

Featured collection

1 of 3